• Walter Vincken
  • Mark L Levy
  • Jane Scullion
  • Omar S Usmani
  • P N Richard Dekhuijzen
  • Chris J Corrigan

We present an extensive review of the literature to date pertaining to the rationale for using a spacer/valved holding chamber (VHC) to deliver inhaled therapy from a pressurised, metered-dose inhaler, a discussion of how the properties of individual devices may vary according to their physical characteristics and materials of manufacture, the potential risks and benefits of ancillaries such as valves, and the evidence that they contribute tangibly to the delivery of therapy. We also reiterate practical recommendations for the correct usage and maintenance of spacers/VHCs, which we trust offer practical help and advice to patients and healthcare professionals alike.

Original languageEnglish
Article number00065-2018
Number of pages10
JournalBMJ Open
Issue number2
Publication statusPublished - Jun 2018

    Research areas

  • spacer, inhaled therapy

ID: 39056714