The new diagnostic criteria for pediatric ME/CFS are structurally based on the
Canadian Clinical Adult case definition, and have more required specific symptoms
than the (Fukuda et al. Ann Intern Med 121:953-959, 1994) adult case definition.
Physicians specializing in pediatric ME/CFS referred thirty-three pediatric
patients with ME/CFS and 21 youth without the illness. Those who met ME/CFS
criteria were separated into Severe and Moderate categories. Significant
differences were found for symptoms within each of the six major categories:
fatigue, post-exertional malaise, sleep, pain, neurocognitive difficulties, and
autonomic/neuroendocrine/immune manifestations. In general, the results showed
participants who met the Severe ME/CFS criteria reported the highest scores, the
Moderate ME/CFS group show scores that were a little lower, and the control group
evidenced the lowest scores. Findings indicate that the Pediatric Case Definition
for ME/CFS can distinguish between those with this illness and controls, and
between those with Severe versus Moderate manifestations of the illness.
Original languageEnglish
Pages (from-to)609-620
Number of pages11
JournalChild Psychiatry Hum Dev.
Issue number4
Publication statusPublished - 10 Jun 2009

    Research areas

  • ME/CFS

ID: 2167457