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SARS-CoV-2 host receptors ACE2 and CD147 (BSG) are present on human oocytes and blastocysts. / Essahib, Wafaa; Verheyen, Greta; Tournaye, Herman; Van de Velde, Hilde.

In: Journal of Assisted Reproduction and Genetics, Vol. 37, No. 11, 11.2020, p. 2657-2660.

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@article{149f3741c7a147c6962d78c32f9b300a,
title = "SARS-CoV-2 host receptors ACE2 and CD147 (BSG) are present on human oocytes and blastocysts",
abstract = "PURPOSE: To visualize SARS-CoV-2 host receptors ACE2 and CD147 on human oocytes and blastocysts.METHODS: Immunohistochemistry and confocal microscopy on human primary oocytes and pre (5 days post fertilization (dpf5) and (dpf6))- and peri (dpf7)-implantation blastocysts donated to research.RESULTS: SARS-CoV-2 host receptors ACE2 and CD147 are present on the membrane of trophectoderm, epiblast and hypoblast cells in human blastocysts. CD147 is also present on the oolemma.CONCLUSION: Theoretically, the earliest stages of embryonic development may be vulnerable for SARS-CoV-2 infection.",
author = "Wafaa Essahib and Greta Verheyen and Herman Tournaye and {Van de Velde}, Hilde",
year = "2020",
month = "11",
doi = "10.1007/s10815-020-01952-x",
language = "English",
volume = "37",
pages = "2657--2660",
journal = "Journal of Assisted Reproduction and Genetics",
issn = "1058-0468",
publisher = "Springer New York",
number = "11",

}

RIS

TY - JOUR

T1 - SARS-CoV-2 host receptors ACE2 and CD147 (BSG) are present on human oocytes and blastocysts

AU - Essahib, Wafaa

AU - Verheyen, Greta

AU - Tournaye, Herman

AU - Van de Velde, Hilde

PY - 2020/11

Y1 - 2020/11

N2 - PURPOSE: To visualize SARS-CoV-2 host receptors ACE2 and CD147 on human oocytes and blastocysts.METHODS: Immunohistochemistry and confocal microscopy on human primary oocytes and pre (5 days post fertilization (dpf5) and (dpf6))- and peri (dpf7)-implantation blastocysts donated to research.RESULTS: SARS-CoV-2 host receptors ACE2 and CD147 are present on the membrane of trophectoderm, epiblast and hypoblast cells in human blastocysts. CD147 is also present on the oolemma.CONCLUSION: Theoretically, the earliest stages of embryonic development may be vulnerable for SARS-CoV-2 infection.

AB - PURPOSE: To visualize SARS-CoV-2 host receptors ACE2 and CD147 on human oocytes and blastocysts.METHODS: Immunohistochemistry and confocal microscopy on human primary oocytes and pre (5 days post fertilization (dpf5) and (dpf6))- and peri (dpf7)-implantation blastocysts donated to research.RESULTS: SARS-CoV-2 host receptors ACE2 and CD147 are present on the membrane of trophectoderm, epiblast and hypoblast cells in human blastocysts. CD147 is also present on the oolemma.CONCLUSION: Theoretically, the earliest stages of embryonic development may be vulnerable for SARS-CoV-2 infection.

UR - http://www.scopus.com/inward/record.url?scp=85091194866&partnerID=8YFLogxK

U2 - 10.1007/s10815-020-01952-x

DO - 10.1007/s10815-020-01952-x

M3 - Article

C2 - 32959144

VL - 37

SP - 2657

EP - 2660

JO - Journal of Assisted Reproduction and Genetics

JF - Journal of Assisted Reproduction and Genetics

SN - 1058-0468

IS - 11

ER -

ID: 53828719