• Chris Baeken
  • Anna-Katharine Brem
  • Martijn Arns
  • Andre R Brunoni
  • Igor Filipčić
  • Ana Ganho-Ávila
  • Berthold Langguth
  • Frank Padberg
  • Emmanuel Poulet
  • Fady Rachid
  • Alexander T Sack
  • Marie-Anne Vanderhasselt
  • Djamila Bennabi

PURPOSE OF REVIEW: After three decades of clinical research on repetitive transcranial magnetic stimulation (rTMS), major depressive disorder (MDD) has proven to be the primary field of application. MDD poses a major challenge for health systems worldwide, emphasizing the need for improving clinical efficacy of existing rTMS applications and promoting the development of novel evidence-based rTMS treatment approaches.

RECENT FINDINGS: Several promising new avenues have been proposed: novel stimulation patterns, targets, and coils; combinatory treatments and maintenance; and personalization and stratification of rTMS parameters, and treatment of subpopulations.

SUMMARY: This opinion review summarizes current knowledge in the field and addresses the future direction of rTMS treatment in MDD, facilitating the establishment of this clinical intervention method as a standard treatment option and continuing to improve response and remission rates, and take the necessary steps to personalize rTMS-based treatment approaches.

Original languageEnglish
Pages (from-to)409-415
Number of pages7
JournalCurrent Opinion in Psychiatry
Issue number5
Publication statusPublished - Sep 2019

    Research areas

  • Repetitive transcranial magnetic stimulation treatment, depressive disorders

ID: 46963782