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Prevalence of metabolic syndrome and its associated risk factors in an African-Caribbean population with severe mental illness. / de Caluwé, Laura; van Buitenen, Nora; Gelan, Petra J; Crunelle, Cleo L; Thomas, Roeland; Casseres, Sharon; Matthys, Frieda; van Harten, Peter; Cahn, Wiepke.

In: Psychiatry Research, Vol. 281, 112558, 01.11.2019.

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de Caluwé, Laura ; van Buitenen, Nora ; Gelan, Petra J ; Crunelle, Cleo L ; Thomas, Roeland ; Casseres, Sharon ; Matthys, Frieda ; van Harten, Peter ; Cahn, Wiepke. / Prevalence of metabolic syndrome and its associated risk factors in an African-Caribbean population with severe mental illness. In: Psychiatry Research. 2019 ; Vol. 281.

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@article{4ab3d4193a914e73949b368dfcac4a51,
title = "Prevalence of metabolic syndrome and its associated risk factors in an African-Caribbean population with severe mental illness",
abstract = "This cross-sectional study aims to determine the prevalence of metabolic syndrome (MetS) in patients with severe mental illness (SMI) on a Caribbean island, Cura{\cc}ao, using the modified National Cholesterol Education Program Adult Treatment Panel III criteria. Among 350 patients (240 men and 110 women) with a mean age of 51.9 years (S.D.=13.5) MetS prevalence was 37.4{\%}, significantly higher in female patients (63.6{\%}) compared to male patients (25.4{\%}). Increased waist circumference was present in 51.1{\%}, low HDL in 50.6{\%}, hypertension in 49.4{\%}, hyperglycemia in 28.6{\%} and 25.7{\%} had hypertriglyceridemia. Except for hypertriglyceridemia, all criteria were more prevalent in female patients. Binary logistic regression analysis indicated that female gender, outpatient treatment setting and the absence of substance use disorder were all significant predictors for MetS. Compared to data from the general population obtained by the 2013 National Health Survey Cura{\cc}ao, this study showed significantly higher prevalence of diabetes and hypertension in patients with SMI. Moreover, female patients had the highest prevalence of diabetes (28.2{\%}), obesity (50.0{\%}) and increased waist circumference (88.2{\%}). This study demonstrates that African-Caribbean patients with SMI are at high-risk for MetS, especially female patients. Our data suggest to focus on modifiable lifestyle risk factors, as promoting physical activity and healthy dietary habits.",
keywords = "Antipsychotic agents, Caribbean region, Diabetes, Metabolic abnormalities, Obesity, Schizophrenia, Sex factors, Substance-related disorders",
author = "{de Caluw{\'e}}, Laura and {van Buitenen}, Nora and Gelan, {Petra J} and Crunelle, {Cleo L} and Roeland Thomas and Sharon Casseres and Frieda Matthys and {van Harten}, Peter and Wiepke Cahn",
note = "Copyright {\circledC} 2019 Elsevier B.V. All rights reserved.",
year = "2019",
month = "11",
day = "1",
doi = "10.1016/j.psychres.2019.112558",
language = "English",
volume = "281",
journal = "Psychiatry Research",
issn = "0165-1781",
publisher = "Elsevier Ireland Ltd",

}

RIS

TY - JOUR

T1 - Prevalence of metabolic syndrome and its associated risk factors in an African-Caribbean population with severe mental illness

AU - de Caluwé, Laura

AU - van Buitenen, Nora

AU - Gelan, Petra J

AU - Crunelle, Cleo L

AU - Thomas, Roeland

AU - Casseres, Sharon

AU - Matthys, Frieda

AU - van Harten, Peter

AU - Cahn, Wiepke

N1 - Copyright © 2019 Elsevier B.V. All rights reserved.

PY - 2019/11/1

Y1 - 2019/11/1

N2 - This cross-sectional study aims to determine the prevalence of metabolic syndrome (MetS) in patients with severe mental illness (SMI) on a Caribbean island, Curaçao, using the modified National Cholesterol Education Program Adult Treatment Panel III criteria. Among 350 patients (240 men and 110 women) with a mean age of 51.9 years (S.D.=13.5) MetS prevalence was 37.4%, significantly higher in female patients (63.6%) compared to male patients (25.4%). Increased waist circumference was present in 51.1%, low HDL in 50.6%, hypertension in 49.4%, hyperglycemia in 28.6% and 25.7% had hypertriglyceridemia. Except for hypertriglyceridemia, all criteria were more prevalent in female patients. Binary logistic regression analysis indicated that female gender, outpatient treatment setting and the absence of substance use disorder were all significant predictors for MetS. Compared to data from the general population obtained by the 2013 National Health Survey Curaçao, this study showed significantly higher prevalence of diabetes and hypertension in patients with SMI. Moreover, female patients had the highest prevalence of diabetes (28.2%), obesity (50.0%) and increased waist circumference (88.2%). This study demonstrates that African-Caribbean patients with SMI are at high-risk for MetS, especially female patients. Our data suggest to focus on modifiable lifestyle risk factors, as promoting physical activity and healthy dietary habits.

AB - This cross-sectional study aims to determine the prevalence of metabolic syndrome (MetS) in patients with severe mental illness (SMI) on a Caribbean island, Curaçao, using the modified National Cholesterol Education Program Adult Treatment Panel III criteria. Among 350 patients (240 men and 110 women) with a mean age of 51.9 years (S.D.=13.5) MetS prevalence was 37.4%, significantly higher in female patients (63.6%) compared to male patients (25.4%). Increased waist circumference was present in 51.1%, low HDL in 50.6%, hypertension in 49.4%, hyperglycemia in 28.6% and 25.7% had hypertriglyceridemia. Except for hypertriglyceridemia, all criteria were more prevalent in female patients. Binary logistic regression analysis indicated that female gender, outpatient treatment setting and the absence of substance use disorder were all significant predictors for MetS. Compared to data from the general population obtained by the 2013 National Health Survey Curaçao, this study showed significantly higher prevalence of diabetes and hypertension in patients with SMI. Moreover, female patients had the highest prevalence of diabetes (28.2%), obesity (50.0%) and increased waist circumference (88.2%). This study demonstrates that African-Caribbean patients with SMI are at high-risk for MetS, especially female patients. Our data suggest to focus on modifiable lifestyle risk factors, as promoting physical activity and healthy dietary habits.

KW - Antipsychotic agents

KW - Caribbean region

KW - Diabetes

KW - Metabolic abnormalities

KW - Obesity

KW - Schizophrenia

KW - Sex factors

KW - Substance-related disorders

UR - http://www.scopus.com/inward/record.url?scp=85072544352&partnerID=8YFLogxK

U2 - 10.1016/j.psychres.2019.112558

DO - 10.1016/j.psychres.2019.112558

M3 - Article

C2 - 31546147

VL - 281

JO - Psychiatry Research

JF - Psychiatry Research

SN - 0165-1781

M1 - 112558

ER -

ID: 47480121