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POSTER: The role of invading immune cells expressing or lacking system xc- in an experimental model for multiple sclerosis. / Merckx, Ellen; Paterka, Magdalena; Van Liefferinge, Joeri; Bentea, Eduard Mihai; Demuyser, Thomas; Albertini, Giulia; Smolders, Ilse Julia; De Keyser, Jacques; Sato, Hideyo; Methner, Axel; Massie, Ann.

Center for Neurosciences PhD Day, Brussels, Belgium, March 13, 2014. 2014.

Research output: Chapter in Book/Report/Conference proceedingMeeting abstract (Book)

Harvard

Merckx, E, Paterka, M, Van Liefferinge, J, Bentea, EM, Demuyser, T, Albertini, G, Smolders, IJ, De Keyser, J, Sato, H, Methner, A & Massie, A 2014, POSTER: The role of invading immune cells expressing or lacking system xc- in an experimental model for multiple sclerosis. in Center for Neurosciences PhD Day, Brussels, Belgium, March 13, 2014. PhD day Center for Neurosciences, Brussels, Belgium, 13/03/14.

APA

Vancouver

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BibTeX

@inbook{3bce19948b4a479f88211b4f7a4bf83c,
title = "POSTER: The role of invading immune cells expressing or lacking system xc- in an experimental model for multiple sclerosis",
abstract = "Multiplesclerosis(MS)isoneofthemostfrequentdisordersofthecentralnervoussystem.Excitotoxicityaswellasoxidativestressarepartofthepathogenesis,inaccordancetootherneurologicaldiseases.Thecystine/glutamateantiporterorsystemxc-,withxCTasspecificsubunit,importscystineinexchangeforglutamateandcanassuchaffectintracellularantioxidantaswellasextracellularglutamatelevels.OxidativestressinducestheexpressionofxCTandcouldconsequentlyaggravateexcitotoxicdamage.Increasedactivityofsystemxc-resultsinprotectionagainstoxidativestress,butatthesametimegivesrisetotoxicextracellularglutamateconcentrations.Withthisprojectweaimatunveilingtheroleofsystemxc-inthepathogenesisofMS.",
author = "Ellen Merckx and Magdalena Paterka and {Van Liefferinge}, Joeri and Bentea, {Eduard Mihai} and Thomas Demuyser and Giulia Albertini and Smolders, {Ilse Julia} and {De Keyser}, Jacques and Hideyo Sato and Axel Methner and Ann Massie",
year = "2014",
language = "English",
booktitle = "Center for Neurosciences PhD Day, Brussels, Belgium, March 13, 2014",

}

RIS

TY - CHAP

T1 - POSTER: The role of invading immune cells expressing or lacking system xc- in an experimental model for multiple sclerosis

AU - Merckx, Ellen

AU - Paterka, Magdalena

AU - Van Liefferinge, Joeri

AU - Bentea, Eduard Mihai

AU - Demuyser, Thomas

AU - Albertini, Giulia

AU - Smolders, Ilse Julia

AU - De Keyser, Jacques

AU - Sato, Hideyo

AU - Methner, Axel

AU - Massie, Ann

PY - 2014

Y1 - 2014

N2 - Multiplesclerosis(MS)isoneofthemostfrequentdisordersofthecentralnervoussystem.Excitotoxicityaswellasoxidativestressarepartofthepathogenesis,inaccordancetootherneurologicaldiseases.Thecystine/glutamateantiporterorsystemxc-,withxCTasspecificsubunit,importscystineinexchangeforglutamateandcanassuchaffectintracellularantioxidantaswellasextracellularglutamatelevels.OxidativestressinducestheexpressionofxCTandcouldconsequentlyaggravateexcitotoxicdamage.Increasedactivityofsystemxc-resultsinprotectionagainstoxidativestress,butatthesametimegivesrisetotoxicextracellularglutamateconcentrations.Withthisprojectweaimatunveilingtheroleofsystemxc-inthepathogenesisofMS.

AB - Multiplesclerosis(MS)isoneofthemostfrequentdisordersofthecentralnervoussystem.Excitotoxicityaswellasoxidativestressarepartofthepathogenesis,inaccordancetootherneurologicaldiseases.Thecystine/glutamateantiporterorsystemxc-,withxCTasspecificsubunit,importscystineinexchangeforglutamateandcanassuchaffectintracellularantioxidantaswellasextracellularglutamatelevels.OxidativestressinducestheexpressionofxCTandcouldconsequentlyaggravateexcitotoxicdamage.Increasedactivityofsystemxc-resultsinprotectionagainstoxidativestress,butatthesametimegivesrisetotoxicextracellularglutamateconcentrations.Withthisprojectweaimatunveilingtheroleofsystemxc-inthepathogenesisofMS.

M3 - Meeting abstract (Book)

BT - Center for Neurosciences PhD Day, Brussels, Belgium, March 13, 2014

ER -

ID: 21646185