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Poly(D, L-Lactic Acid) (PDLLA) Biodegradable and Biocompatible Polymer Optical Fiber. / Gierej, Agnieszka; Vagenende, Maxime; Filipkowski, A.; Siwicki, Bartlotniej; Buczynski, R.; Thienpont, Hugo; Van Vlierberghe, Sandra; Geernaert, Thomas; Dubruel, P.; Berghmans, Francis.

In: Journal of Lightwave Technology, Vol. 37, No. 9, 8631010, 01.05.2019, p. 1916-1923.

Research output: Contribution to journalArticleResearchpeer-review

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Gierej A, Vagenende M, Filipkowski A, Siwicki B, Buczynski R, Thienpont H et al. Poly(D, L-Lactic Acid) (PDLLA) Biodegradable and Biocompatible Polymer Optical Fiber. Journal of Lightwave Technology. 2019 May 1;37(9):1916-1923. 8631010. https://doi.org/10.1109/JLT.2019.2895220

Author

Gierej, Agnieszka ; Vagenende, Maxime ; Filipkowski, A. ; Siwicki, Bartlotniej ; Buczynski, R. ; Thienpont, Hugo ; Van Vlierberghe, Sandra ; Geernaert, Thomas ; Dubruel, P. ; Berghmans, Francis. / Poly(D, L-Lactic Acid) (PDLLA) Biodegradable and Biocompatible Polymer Optical Fiber. In: Journal of Lightwave Technology. 2019 ; Vol. 37, No. 9. pp. 1916-1923.

BibTeX

@article{1cb4d38b2d0a47f8890145ddaf28f412,
title = "Poly(D, L-Lactic Acid) (PDLLA) Biodegradable and Biocompatible Polymer Optical Fiber",
abstract = "We demonstrate that commercially available poly(D,L-lactic acid) (PDLLA) is a suitable material for the fabrication of biodegradable optical fibers with a standard heat drawing process. To do so we report on the chemical and optical characterization of the material. We address the influence of the polymer processing on the molecular weight and thermal properties of the polymer following the preparation of the polymer preforms and the fiber optic drawing process. We show that cutback measurements of the first optical fibers drawn from PDLLA return an attenuation coefficient as low as 0.11 dB/cm at 772 nm, which is the lowest loss reported this far for optical fibers drawn from bio-resorbable material. We also report on the dispersion characteristics of PDLLA, and we find that the thermo-optic coefficient is in the range of -10 -4 °C -1 . Finally, we studied the degradation of PDLLA fibers in vitro, revealing that fibers with the largest diameter of 600 μm degrade faster than those with smaller diameters of 300 and 200 μm and feature more than 84{\%} molecular weight loss over a period of 3 months. The evolution of the optical loss of the fibers as a function of time during immersion in phosphate-buffered saline indicates that these devices are potential candidates for use in photodynamic therapy-like application scenarios.",
keywords = "Biodegradable materials, optical polymers, plastic optical fiber",
author = "Agnieszka Gierej and Maxime Vagenende and A. Filipkowski and Bartlotniej Siwicki and R. Buczynski and Hugo Thienpont and {Van Vlierberghe}, Sandra and Thomas Geernaert and P. Dubruel and Francis Berghmans",
year = "2019",
month = "5",
day = "1",
doi = "10.1109/JLT.2019.2895220",
language = "English",
volume = "37",
pages = "1916--1923",
journal = "Journal of Lightwave Technology",
issn = "0733-8724",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
number = "9",

}

RIS

TY - JOUR

T1 - Poly(D, L-Lactic Acid) (PDLLA) Biodegradable and Biocompatible Polymer Optical Fiber

AU - Gierej, Agnieszka

AU - Vagenende, Maxime

AU - Filipkowski, A.

AU - Siwicki, Bartlotniej

AU - Buczynski, R.

AU - Thienpont, Hugo

AU - Van Vlierberghe, Sandra

AU - Geernaert, Thomas

AU - Dubruel, P.

AU - Berghmans, Francis

PY - 2019/5/1

Y1 - 2019/5/1

N2 - We demonstrate that commercially available poly(D,L-lactic acid) (PDLLA) is a suitable material for the fabrication of biodegradable optical fibers with a standard heat drawing process. To do so we report on the chemical and optical characterization of the material. We address the influence of the polymer processing on the molecular weight and thermal properties of the polymer following the preparation of the polymer preforms and the fiber optic drawing process. We show that cutback measurements of the first optical fibers drawn from PDLLA return an attenuation coefficient as low as 0.11 dB/cm at 772 nm, which is the lowest loss reported this far for optical fibers drawn from bio-resorbable material. We also report on the dispersion characteristics of PDLLA, and we find that the thermo-optic coefficient is in the range of -10 -4 °C -1 . Finally, we studied the degradation of PDLLA fibers in vitro, revealing that fibers with the largest diameter of 600 μm degrade faster than those with smaller diameters of 300 and 200 μm and feature more than 84% molecular weight loss over a period of 3 months. The evolution of the optical loss of the fibers as a function of time during immersion in phosphate-buffered saline indicates that these devices are potential candidates for use in photodynamic therapy-like application scenarios.

AB - We demonstrate that commercially available poly(D,L-lactic acid) (PDLLA) is a suitable material for the fabrication of biodegradable optical fibers with a standard heat drawing process. To do so we report on the chemical and optical characterization of the material. We address the influence of the polymer processing on the molecular weight and thermal properties of the polymer following the preparation of the polymer preforms and the fiber optic drawing process. We show that cutback measurements of the first optical fibers drawn from PDLLA return an attenuation coefficient as low as 0.11 dB/cm at 772 nm, which is the lowest loss reported this far for optical fibers drawn from bio-resorbable material. We also report on the dispersion characteristics of PDLLA, and we find that the thermo-optic coefficient is in the range of -10 -4 °C -1 . Finally, we studied the degradation of PDLLA fibers in vitro, revealing that fibers with the largest diameter of 600 μm degrade faster than those with smaller diameters of 300 and 200 μm and feature more than 84% molecular weight loss over a period of 3 months. The evolution of the optical loss of the fibers as a function of time during immersion in phosphate-buffered saline indicates that these devices are potential candidates for use in photodynamic therapy-like application scenarios.

KW - Biodegradable materials

KW - optical polymers

KW - plastic optical fiber

UR - http://www.scopus.com/inward/record.url?scp=85064656722&partnerID=8YFLogxK

U2 - 10.1109/JLT.2019.2895220

DO - 10.1109/JLT.2019.2895220

M3 - Article

VL - 37

SP - 1916

EP - 1923

JO - Journal of Lightwave Technology

JF - Journal of Lightwave Technology

SN - 0733-8724

IS - 9

M1 - 8631010

ER -

ID: 45604153