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Performance evaluation of the Diasorin LIAISON® XL Zika capture IgM CLIA test. / Van der Beken, Y; De Geyter, D; Van Esbroeck, M.

In: Diagnostic Microbiology and Infectious Disease, Vol. 95, No. 2, 2019, p. 144-148.

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Van der Beken, Y, De Geyter, D & Van Esbroeck, M 2019, 'Performance evaluation of the Diasorin LIAISON® XL Zika capture IgM CLIA test', Diagnostic Microbiology and Infectious Disease, vol. 95, no. 2, pp. 144-148. https://doi.org/10.1016/j.diagmicrobio.2019.05.004

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Van der Beken, Y ; De Geyter, D ; Van Esbroeck, M. / Performance evaluation of the Diasorin LIAISON® XL Zika capture IgM CLIA test. In: Diagnostic Microbiology and Infectious Disease. 2019 ; Vol. 95, No. 2. pp. 144-148.

BibTeX

@article{477485183e7349ea83da0e991544f3d5,
title = "Performance evaluation of the Diasorin LIAISON{\circledR} XL Zika capture IgM CLIA test",
abstract = "Because Zika virus (ZIKV) can cause serious birth defects and is involved in cases of Guillain-Barr{\'e} syndrome, the ZIKV outbreak in the American continent in 2015 resulted in an enormous need for ZIKV diagnostic tools. We evaluated the LIAISON{\circledR} XL Zika Capture IgM test on 106 samples from patients, mainly travelers, with a confirmed or probable ZIKV infection. Sensitivity between 0 and 84 days after onset of symptoms was 92.5{\%}. Specificity was evaluated on a panel of 56 samples known to cause possible cross-reactions. Cross-reaction with DENV antibodies was limited (10.5{\%}) but false-positive results occurred in samples from patients with malaria, CMV and EBV infections.",
keywords = "Antibodies, Viral/blood, Automation, Laboratory, Cross Reactions, Humans, Immunoglobulin M/blood, Retrospective Studies, Sensitivity and Specificity, Serologic Tests/methods, Zika Virus/immunology, Zika Virus Infection/blood",
author = "{Van der Beken}, Y and {De Geyter}, D and {Van Esbroeck}, M",
note = "Copyright {\circledC} 2019 Elsevier Inc. All rights reserved.",
year = "2019",
doi = "10.1016/j.diagmicrobio.2019.05.004",
language = "English",
volume = "95",
pages = "144--148",
journal = "Diagnostic Microbiology and Infectious Disease",
issn = "0732-8893",
publisher = "Elsevier Inc.",
number = "2",

}

RIS

TY - JOUR

T1 - Performance evaluation of the Diasorin LIAISON® XL Zika capture IgM CLIA test

AU - Van der Beken, Y

AU - De Geyter, D

AU - Van Esbroeck, M

N1 - Copyright © 2019 Elsevier Inc. All rights reserved.

PY - 2019

Y1 - 2019

N2 - Because Zika virus (ZIKV) can cause serious birth defects and is involved in cases of Guillain-Barré syndrome, the ZIKV outbreak in the American continent in 2015 resulted in an enormous need for ZIKV diagnostic tools. We evaluated the LIAISON® XL Zika Capture IgM test on 106 samples from patients, mainly travelers, with a confirmed or probable ZIKV infection. Sensitivity between 0 and 84 days after onset of symptoms was 92.5%. Specificity was evaluated on a panel of 56 samples known to cause possible cross-reactions. Cross-reaction with DENV antibodies was limited (10.5%) but false-positive results occurred in samples from patients with malaria, CMV and EBV infections.

AB - Because Zika virus (ZIKV) can cause serious birth defects and is involved in cases of Guillain-Barré syndrome, the ZIKV outbreak in the American continent in 2015 resulted in an enormous need for ZIKV diagnostic tools. We evaluated the LIAISON® XL Zika Capture IgM test on 106 samples from patients, mainly travelers, with a confirmed or probable ZIKV infection. Sensitivity between 0 and 84 days after onset of symptoms was 92.5%. Specificity was evaluated on a panel of 56 samples known to cause possible cross-reactions. Cross-reaction with DENV antibodies was limited (10.5%) but false-positive results occurred in samples from patients with malaria, CMV and EBV infections.

KW - Antibodies, Viral/blood

KW - Automation, Laboratory

KW - Cross Reactions

KW - Humans

KW - Immunoglobulin M/blood

KW - Retrospective Studies

KW - Sensitivity and Specificity

KW - Serologic Tests/methods

KW - Zika Virus/immunology

KW - Zika Virus Infection/blood

U2 - 10.1016/j.diagmicrobio.2019.05.004

DO - 10.1016/j.diagmicrobio.2019.05.004

M3 - Article

C2 - 31171395

VL - 95

SP - 144

EP - 148

JO - Diagnostic Microbiology and Infectious Disease

JF - Diagnostic Microbiology and Infectious Disease

SN - 0732-8893

IS - 2

ER -

ID: 49211956