Standard

Neuroanatomical Reconstruction of the Canine Visual Pathway Using Diffusion Tensor Imaging. / Jacqmot, Olivier; Van Thielen, Bert; Michotte, Alex; de Mey, Johan; Provyn, Steven; Tresignie, Jonathan.

In: Frontiers in neuroanatomy, Vol. 14, 54, 2020.

Research output: Contribution to journalArticle

Harvard

APA

Vancouver

Author

BibTeX

@article{21ea74342c0e48579347afca4efbd8be,
title = "Neuroanatomical Reconstruction of the Canine Visual Pathway Using Diffusion Tensor Imaging",
abstract = "The first anatomical atlas of diffusion tensor imaging (DTI) of white matter pathways in the canine brain was published in 2013; however, the anatomical orientation of the entire visual pathway in the canine brain, from the retina to the cortex, has not yet been studied using DTI. In the present study, 3T DTI magnetic resonance (MR) images of three dogs euthanized for reasons other than neurological disorders were obtained. The process of obtaining combined fractional anisotropy and directional maps was initiated within 1 h of death. The heads were amputated immediately after MR imaging and stored in 10{\%} formalin until dissection and histological sampling was performed. The trajectory of the visual pathway is dissimilar to the horizontal representation in other literature. To our knowledge, ours is the first study to visualize the entire canine visual pathway in its full antero-posterior extension. Fibers from the retina to the cortex passed through the optic nerve, optic chiasm, optic tracts, lateral geniculate nucleus, Meyer's and Baum's loops, and pretectal fibers. Their projections to the cortex were similar to those in the human visual pathway. The crossing of fibers at the optic chiasm occurred in 75{\%} of fibers. In addition to advancing our knowledge in this field of study, these results could help plan neurosurgical and radiotherapeutic procedures to avoid unnecessary damage to the visual fiber system.",
keywords = "DTI, MRI, canine, stereotaxy, visual pathway",
author = "Olivier Jacqmot and {Van Thielen}, Bert and Alex Michotte and {de Mey}, Johan and Steven Provyn and Jonathan Tresignie",
note = "Copyright {\circledC} 2020 Jacqmot, Van Thielen, Michotte, de Mey, Provyn and Tresignie.",
year = "2020",
doi = "10.3389/fnana.2020.00054",
language = "English",
volume = "14",
journal = "Frontiers in neuroanatomy",
issn = "1662-5129",

}

RIS

TY - JOUR

T1 - Neuroanatomical Reconstruction of the Canine Visual Pathway Using Diffusion Tensor Imaging

AU - Jacqmot, Olivier

AU - Van Thielen, Bert

AU - Michotte, Alex

AU - de Mey, Johan

AU - Provyn, Steven

AU - Tresignie, Jonathan

N1 - Copyright © 2020 Jacqmot, Van Thielen, Michotte, de Mey, Provyn and Tresignie.

PY - 2020

Y1 - 2020

N2 - The first anatomical atlas of diffusion tensor imaging (DTI) of white matter pathways in the canine brain was published in 2013; however, the anatomical orientation of the entire visual pathway in the canine brain, from the retina to the cortex, has not yet been studied using DTI. In the present study, 3T DTI magnetic resonance (MR) images of three dogs euthanized for reasons other than neurological disorders were obtained. The process of obtaining combined fractional anisotropy and directional maps was initiated within 1 h of death. The heads were amputated immediately after MR imaging and stored in 10% formalin until dissection and histological sampling was performed. The trajectory of the visual pathway is dissimilar to the horizontal representation in other literature. To our knowledge, ours is the first study to visualize the entire canine visual pathway in its full antero-posterior extension. Fibers from the retina to the cortex passed through the optic nerve, optic chiasm, optic tracts, lateral geniculate nucleus, Meyer's and Baum's loops, and pretectal fibers. Their projections to the cortex were similar to those in the human visual pathway. The crossing of fibers at the optic chiasm occurred in 75% of fibers. In addition to advancing our knowledge in this field of study, these results could help plan neurosurgical and radiotherapeutic procedures to avoid unnecessary damage to the visual fiber system.

AB - The first anatomical atlas of diffusion tensor imaging (DTI) of white matter pathways in the canine brain was published in 2013; however, the anatomical orientation of the entire visual pathway in the canine brain, from the retina to the cortex, has not yet been studied using DTI. In the present study, 3T DTI magnetic resonance (MR) images of three dogs euthanized for reasons other than neurological disorders were obtained. The process of obtaining combined fractional anisotropy and directional maps was initiated within 1 h of death. The heads were amputated immediately after MR imaging and stored in 10% formalin until dissection and histological sampling was performed. The trajectory of the visual pathway is dissimilar to the horizontal representation in other literature. To our knowledge, ours is the first study to visualize the entire canine visual pathway in its full antero-posterior extension. Fibers from the retina to the cortex passed through the optic nerve, optic chiasm, optic tracts, lateral geniculate nucleus, Meyer's and Baum's loops, and pretectal fibers. Their projections to the cortex were similar to those in the human visual pathway. The crossing of fibers at the optic chiasm occurred in 75% of fibers. In addition to advancing our knowledge in this field of study, these results could help plan neurosurgical and radiotherapeutic procedures to avoid unnecessary damage to the visual fiber system.

KW - DTI

KW - MRI

KW - canine

KW - stereotaxy

KW - visual pathway

U2 - 10.3389/fnana.2020.00054

DO - 10.3389/fnana.2020.00054

M3 - Article

C2 - 32973464

VL - 14

JO - Frontiers in neuroanatomy

JF - Frontiers in neuroanatomy

SN - 1662-5129

M1 - 54

ER -

ID: 53824176