• Ingo Beyer
  • R Karmali
  • N Demeester-Mirkine
  • Elie Cogan
  • M. Fuss
It is admitted that serum creatine kinase (CK) of skeletal muscle origin is increased in patients with overt hypothyroidism, a fact we have also observed in such patients. Our observations further suggest that this may also be the case to some extent in subclinical hypothyroidism. Monzani et al. thus demonstrated muscular abnormalities during exercise in sHT apparently related to the duration of this condition. In our cross-sectional analysis in patients at rest the statistical significance of the relationship between a biological parameter easy to measure, serum CK activity, and the degree of sHT sustains the hypothesis of muscular impairment.
Original languageEnglish
Pages (from-to)1823
Number of pages1
JournalJ Clin Endocrinol Metab
Volume83
Publication statusPublished - May 1998

    Research areas

  • hypothyroidism, subclinical, creatine kinase (CK)

ID: 2152309