Fluid flow was simulated in a human mouth-throat model under normal breathing conditions (30 l/min) alternatively employing
RANS k-w (without near-wall corrections), DES and LES methods. To test the validity of the fluid phase simulations, PIV
measurements were carried out in a central sagittal plane of an identical model cast. Velocity and kinetic-energy profiles showed
good quantitative agreement of experiments with LES/DES, and less so with RANS k-w. Mouth-throat deposition was simulated for
particle diameters 2, 4, 6, 8 and 10 micrometer. By comparison with existing experimental data, LES/DES showed considerable improvement
over the RANS k-w model in predicting deposition for particle sizes below 5 micrometer. For the bigger particles, RANS k-w and LES/DES
methods produced similarly good predictions. It is concluded that for the simulation of medication aerosols inhaled at a steady flow
rate of 30 l/min, LES and DES provide more accurate results than the RANS k-w model tested.
Original languageEnglish
Pages (from-to)862-875
Number of pages14
JournalJournal of Aerosol Science
Volume39
Publication statusPublished - 2 Jun 2008

    Research areas

  • Mouth-throat model, Particle image velocimetry (PIV), Large eddy simulation (LES), Detached eddy simulation (DES), Particle deposition

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