Objectives: To analyze the hand grip strength (HGS) in relation tonutritional and pulmonary status in children and adolescents with cysticfibrosis (CF).Methods: Hand grip data of CF children (aged 5–15 years) having abody composition and lung function measurement at a yearly follow upwere analyzed. Body fat percentage (FM%) calculated from skin foldmeasurements using the method of Slaughter, was expressed as centilefrom the NHANES IV database (FM% centile). Z-scores for weight (WFA),height (HFA), body mass index (BMI) and mid-upper arm circumference(MUAC) were calculated using Belgian reference data. HGS wasexpressed as a percentage of the mean value of Belgian reference datafor the according age (%HGS). Forced vital capacity (FVC) and forcedexpiratory volumes in one second (FEV1) were expressed as % for ageand body height.Results: HGS was assessed 269 times in 60 (24 female) patients (6 (10.3%)pancreas sufficient). Their mean (95% CI) WFA, HFA, BMI and MUAC zscoreswere −0.60 (−0.71;−0.48), −0.38 (−0.49;−0.26), −0.58 (−0.70;−0.45) and −0.59 (−0.70;−0.47) and their median (Q1;Q3) FM% centile andFEV1 were 50 (25;50) and 97% (84.8%;105.7). Median (Q1;Q3) %HGS was72.4% (58.7%;85.4%). %HGS was not different according to sex (p = 0.696)and pancreas involvement (p = 0.561). %HGS correlated significantly(p < 0.001) with WFA (r = 0.517), HFA (r = 0.459), BMI (r = 0.392) andMUAC (r = 0.402) and FEV1(r = 0.325), but not with FM% centile (ρ = 0.10;p = 0.873). Stepwise linear regression showed that %HGF was significantly(F = 35.6, p < 0.001; r² = 0.34) predicted by HFA (β = 0.368), FVC (β = 0.181),age (β = 0.145) and BMI (β = 0.236).Conclusion: CF children and adolescents have a lower handgrip force inaccordance with their nutritional status assessed by standard anthropometry,irrespective of their pulmonary status.
Original languageEnglish
Pages (from-to)S150-S150
JournalJournal of Cystic Fibrosis
Issue numberS1
Publication statusPublished - Jun 2017
Event40th annual meeting of ECFS - Seville, Seville, Spain
Duration: 6 Jun 201710 Jun 2017

    Research areas

  • hadgrip force, CF children and adolescents, impact, nutritional and pulmonary status

ID: 36286746