We present a case of persistent fetal supraventricular tachycardia where transplacental and direct fetal treatment with amiodarone caused an iatrogenic hypothyroidism. This condition was successfully managed with the intra-amniotic instillation of 250 micrograms of L-thyroxine weekly, for 3 weeks. A male infant was delivered at 32 weeks by Caesarean section. The neonatal electrocardiogram showed Wolf-Parkinson-White (WPW) syndrome, which was controlled by digoxin alone. Thyroid function normalized quickly and the baby is developing normally.
Original languageEnglish
Pages (from-to)762-765
Number of pages4
JournalPrenat Diagn
Volume14
Issue numberAugustus
Publication statusPublished - Aug 1994

    Research areas

  • Fetal hypothyroidism, Fetal Diseases, Drug therapy, supraventricular tachycardia

ID: 1075522