Faculty of Medicine and Pharmacy

Postal address
Pleinlaan 2
1050
Brussel
Belgium

Basic (bio-) Medical Sciences

Postal address
Laarbeeklaan 103
1090
Brussels
Belgium

Expertise

Yannick De Vlaeminck finished his Bachelor as a Medical Lab Technician in 2008 at the Erasmus Hogeschool Brussels and started to work in the field of neurogenetics, cardiogentics and mitochondrial diseases (Centre of Medical Genetics, UZBrussel). As he expanded his practical skills, he gradually started to participate more and more in research projects. This enabled him to develop a scientific and critical way of thinking. This experience motivated him to obtain a Master degree in Biomedical Sciences and as such pursue a research career.

During his internship of the final year Master in Biomedical Sciences (VUB, 2014-2015) at the LMCT, he was in charge of setting up a novel project in which he used state-of-the-art tools such as lentiviral vectors and nanobodies to target tumor-associated macrophages (TAMs). The insights he gained on how lentiviral vectors and nanobodies marriage together as a successful couple for cell targeting, and how the function of TAMs can be manipulated through lentiviral-mediated delivery of a SMAC mimetic, laid the foundation for his VLK/ORC/FWO-SB funded PhD project (VUB, 2015-2020) at LMCT.  

During his PhD he gained experience in molecular cloning, single domain antibody production/purification, gene therapy approaches using lentiviral vectors and macrophage biology.

Research output

  1. Theranostics in immuno-oncology using nanobody derivatives

    Research output: Contribution to journalScientific reviewResearchpeer-review

  2. Theranostics in immuno-oncology using nanobody derivatives

    Research output: Contribution to journalSpecial issueResearch

  3. Noninvasive Imaging of the Immune Checkpoint LAG-3 Using Nanobodies, from Development to Pre-Clinical Use

    Research output: Contribution to journalArticleResearchpeer-review

View all (23) »

Activities

  1. Nanobody-mediated imaging of the immune checkpoint LAG-3

    Activity: Talk or presentationTalk or presentation at a conference

  2. Single domain antibody-mediated imaging of the mouse immune checkpoint LAG-3

    Activity: Talk or presentationTalk or presentation at a conference

View all (2) »

Prizes

  1. ORC DAY best poster

    Prize: Prize (including medals and awards)

  2. Granted FWO fellowship

    Prize: Fellowship awarded competitively

View all (7) »

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