Pharmaceutical and Pharmacological Sciences

Postal address
Laarbeeklaan 103
1090
Jette
Belgium

Expertise

Basic research related to the development of in vitro alternative methods:

  • Human liver-based in vitro models
  • Adult human skin-derived progenitor cells and their hepatic derivatives
  • DILI screening, including steatosis, phospholipidosis and acute liver failure
  • Flow cytometry-based high throughput screening of various hepatic cell models, for live/dead cell analysis, lipid and phospholipid accumulation
  • Microscopy-based high content analysis for lipid and mitochondrial deregulation analysis
  • Genotoxicant-specific qPCR array
  • Transcriptomics and metabolomics readouts and analysis
  • Risk assessment of consumer products

Activities

  1. Application of a human skin stem cell-derived in vitro liver model of non-alcoholic steatohepatitis

    Activity: Talk or presentationTalk or presentation at a conference

  2. Untargeted in vitro metabolomics to identify hepatotoxic models of action

    Activity: Talk or presentationTalk or presentation at a conference

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Prizes

  1. Best Paper Award 2007 from the Toxicological Society

    Prize: Prize (including medals and awards)

  2. Prize of the Foundation Prince Louis de Polignac

    Prize: Prize (including medals and awards)

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