Pathology/molecular and cellular medicine

Postal address
Laarbeeklaan 101
1090
Brussels
Belgium

Expertise

MD PhD with expertise in deep phenotyping using various OMICS  tools (genomics, transcriptomics, metabolomics, proteomics) for cell biology and IVD applications. 

 

MD with specific expertise in: (i) biochemical diagnosis of inborn errors of metabolism using chromatographic techniques; (ii) molecular diagnostics: genomic analysis of solid and hematological tumors using DNA/RNA sequencing and qPCR and prenatal diagnosis using genome wide NIPT; (iii) clinical validation of bioinformatic pipelines.

 

Researcher with specific expertise in (i) beta cell therapy in type 1 diabetes & deep phenotyping of pancreatic beta cells in vitro; (ii) cell biology of beta cell death & differentiation; (iii) metabolomic profiling of extreme metabolic phenotypes using high-resolution metabolimics on Waters VION IMS QTOF; (iv) biomarker identification and prototype assay development (high-sensitivity immunoassays for protein biomarkers and targeted PCR for DNA or microRNA markers); (v) integrated profiling of pathogenic variants in tumors. 

 

Senior lecturer at Vrije Universiteit Brussel (Course: Integrative physiology and systems biology, 3rd bachelor medical school)

 

Independent consultant at AZ Delta general hospital. 

Research output

  1. Clinical implementation of gene panel testing for lysosomal storage diseases

    Research output: Contribution to journalArticleResearchpeer-review

  2. Combined Analysis of GAD65, miR-375, and Unmethylated Insulin DNA Following Islet Transplantation in Patients With T1D

    Research output: Contribution to journalArticleResearchpeer-review

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Activities

  1. Erfelijke Stofwisselingsziekten Nederland (External organisation)

    Activity: MembershipMembership of external research organisation

  2. European Association for the Study of Diabetes (EASD) (External organisation)

    Activity: MembershipMembership of external research organisation

  3. Society for the Study of Inborn Errors of Metabolism (SSIEM) (External organisation)

    Activity: MembershipMembership of public/government advisory/policy group or panel

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Prizes

  1. SSIEM

    Prize: Fellowship awarded competitively

  2. Aspirant FWO

    Prize: Prize (including medals and awards)

  3. Pfizer Educational Award

    Prize: Prize (including medals and awards)

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