Pierre Philippe Gelin - Speaker

Iwona Ziemecka - Contributor

Kris Pauwels - Contributor

Marzena Krzek - Contributor

Özlem Sardan Sukas - Contributor

Peter Tompa - Contributor

Dominique Maes - Contributor

Wim De Malsche - Contributor

Microfluidic devices offer a well-controlled environment for crystal nucleation and growth. Important parameters are mixing and the associated shear. Incomplete or insufficient mixing results in a wide crystal size distribution and might affect the morphology and purity of the product. Bulk acoustic waves offer the possibility to quickly mix two liquid streams and to manipulate particles in the microfluidic channel. In this contribution, fast mixing of two liquid streams by acoustic streaming is demonstrated. Miconazole nitrate crystals were grown in the presence of the acoustic field, once a desired size is reached the crystals focus rapidly on the pressure node. Growth and focusing of amyloid fibrils in the microfluidic channel has also been demonstrated.
11 Nov 201815 Nov 2018

Event (Conference)

Title22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2018)
Abbrev. TitleµTAS 2018
Web address (URL)
CountryTaiwan, Province of China
Degree of recognitionInternational event

ID: 39056899